About Cleft
Cleft Research
Operation Smile conducts impactful research to enhance both surgical and nonsurgical care for patients and families.
Ensuring a Lasting Impact
Our focus is on improving quality of life through evidence-based programs and influencing global health systems and policies.
Our research spans various areas, from cleft-specific care to broader surgical topics like epidemiology, genetics, outcomes, leadership, and education. We aim to understand the causes of cleft lip and palate to develop preventive measures for future generations, ensuring a lasting impact on cleft care.


Explore Research Collaborated with or Conducted by our Global Operation Smile Team
The Smile Index: Part 3. A Simple, Prognostic Severity Scale for Unilateral Cleft Palate
Authors: Yao CA, Vartanian ED, Nagengast E, McCullough M, Auslander A, Magee WP 3rd.
Convolutional Neural Network Models for Automatic Preoperative Severity Assessment in Unilateral Cleft Lip
Authors: McCullough M, Ly S, Auslander A, Yao C, Campbell A, Scherer S, Magee WP 3rd.
Clinical and Descriptive Study of Orofacial Clefts in Colombia: 2069 Patients From Operation Smile Foundation
Authors: Espinosa, A. S., Martinez, J. C., Molina, Y., Gordillo, M., Hernández, D. R., Rivera, D. Z., Olmos, B. P., Ramírez, N., Arias, L., Zarate, A., Diana Marcela Diaz, Q., Collins, A., Cepeda, Á., & Balcazar, I. B.
The Use of Crowdsourcing Technology to Evaluate Preoperative Severity in Patients With Unilateral Cleft Lip in a Multiethnic Population
Authors: McCullough, M., Auslander, A., Nagengast, E. S., Yao, C. A., Swanson, J. W., & Magee, W. P., 3rd
Modified Buccal Myomucosal Flap Closure of Large Anterior Palatal Oronasal Fistulas
Authors: Kalmar, C. L., Siu, A., Alvarez, E., & Swanson, J. W.
The Smile Index: Part 2. A Simple, Prognostic Severity Scale for Unilateral Cleft Lip
Authors: Yao, C. A., McCullough, M., Auslander, A., Imahiyerobo, T. A., Vander Burg, R., & Magee, W. P. III.