About Cleft

Cleft Research

Operation Smile conducts impactful research to enhance both surgical and nonsurgical care for patients and families.

Ensuring a Lasting Impact

Our focus is on improving quality of life through evidence-based programs and influencing global health systems and policies.

Our research spans various areas, from cleft-specific care to broader surgical topics like epidemiology, genetics, outcomes, leadership, and education. We aim to understand the causes of cleft lip and palate to develop preventive measures for future generations, ensuring a lasting impact on cleft care.

Explore Research Collaborated with or Conducted by our Global Operation Smile Team

Plastic and Reconstructive Surgery - Global Open – 2021

The Smile Index: Part 3. A Simple, Prognostic Severity Scale for Unilateral Cleft Palate

Authors: Yao CA, Vartanian ED, Nagengast E, McCullough M, Auslander A, Magee WP 3rd.

Plastic and Reconstructive Surgery – 2021

Convolutional Neural Network Models for Automatic Preoperative Severity Assessment in Unilateral Cleft Lip

Authors: McCullough M, Ly S, Auslander A, Yao C, Campbell A, Scherer S, Magee WP 3rd.

The Cleft Palate-Craniofacial Journal – 2021

Clinical and Descriptive Study of Orofacial Clefts in Colombia: 2069 Patients From Operation Smile Foundation

Authors: Espinosa, A. S., Martinez, J. C., Molina, Y., Gordillo, M., Hernández, D. R., Rivera, D. Z., Olmos, B. P., Ramírez, N., Arias, L., Zarate, A., Diana Marcela Diaz, Q., Collins, A., Cepeda, Á., & Balcazar, I. B.

The Journal of craniofacial surgery – 2021

The Use of Crowdsourcing Technology to Evaluate Preoperative Severity in Patients With Unilateral Cleft Lip in a Multiethnic Population

Authors: McCullough, M., Auslander, A., Nagengast, E. S., Yao, C. A., Swanson, J. W., & Magee, W. P., 3rd

Plastic and Reconstructive Surgery – 2021

Modified Buccal Myomucosal Flap Closure of Large Anterior Palatal Oronasal Fistulas

Authors: Kalmar, C. L., Siu, A., Alvarez, E., & Swanson, J. W.

Plastic and Reconstructive Surgery – 2019

The Smile Index: Part 2. A Simple, Prognostic Severity Scale for Unilateral Cleft Lip

Authors: Yao, C. A., McCullough, M., Auslander, A., Imahiyerobo, T. A., Vander Burg, R., & Magee, W. P. III.

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